Emma Di Carlo Selected Research

Interleukin-12 (IL 12)

10/2010	Direct inhibition of human acute myeloid leukemia cell growth by IL-12.
7/2009	IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions.
8/2008	Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target.
7/2007	Inhibition of prostate carcinogenesis by combined active immunoprophylaxis.
3/2007	Endogenous IL-12 triggers an antiangiogenic program in melanoma cells.
6/2006	Timely DNA vaccine combined with systemic IL-12 prevents parotid carcinomas before a dominant-negative p53 makes their growth independent of HER-2/neu expression.
4/2006	Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells.
12/2005	Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy.
3/2005	Cure of mammary carcinomas in Her-2 transgenic mice through sequential stimulation of innate (neoadjuvant interleukin-12) and adaptive (DNA vaccine electroporation) immunity.
11/2004	Immunological prevention of a multigene cancer syndrome.

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Emma Di Carlo Research Topics

Disease

43	Neoplasms (Cancer) 02/2022 - 07/2002
10	Carcinoma (Carcinomatosis) 06/2006 - 01/2003
9	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 05/2009
9	Carcinogenesis 01/2016 - 05/2003
6	Adenocarcinoma 01/2016 - 07/2002
5	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2003
5	Breast Neoplasms (Breast Cancer) 01/2021 - 06/2004
2	Neuroblastoma 01/2017 - 05/2013
2	Lymphatic Metastasis 03/2016 - 10/2009
2	Inflammation (Inflammations) 08/2015 - 03/2014
2	Necrosis 02/2015 - 11/2014
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 03/2012 - 10/2010
2	Colitis 11/2007 - 04/2004
2	Glomerulonephritis 12/2005 - 11/2003
1	Chromosome Aberrations (Chromosome Abnormalities) 09/2021
1	Fanconi Anemia (Fanconi's Anemia) 09/2021
1	Hematologic Neoplasms (Hematological Malignancy) 01/2017
1	Disease Progression 01/2016
1	Communicable Diseases (Infectious Diseases) 10/2015
1	B-Cell Lymphoma (Lymphoma, B Cell) 10/2015
1	Adenoma (Adenomas) 08/2015
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2015
1	Seroma 04/2014
1	Colonic Neoplasms (Colon Cancer) 01/2014
1	Leukemia 03/2012
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/2010
1	Multiple Myeloma 08/2010
1	Lung Neoplasms (Lung Cancer) 10/2009
1	Adenocarcinoma of Lung 07/2009
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 08/2008
1	Plasmacytoma 08/2008
1	Lymphoma (Lymphomas) 08/2008

Drug/Important Bio-Agent (IBA)

17	Interleukin-12 (IL 12)IBA 10/2010 - 07/2002
16	CytokinesIBA 01/2021 - 07/2002
7	VaccinesIBA 07/2007 - 01/2003
6	Interleukin-6 (Interleukin 6)IBA 11/2016 - 12/2005
5	DNA (Deoxyribonucleic Acid)IBA 09/2021 - 05/2003
5	InterleukinsIBA 01/2019 - 06/2004
5	Interleukin-27 (Interleukin 27)IBA 02/2015 - 08/2010
5	Proteins (Proteins, Gene)FDA Link 11/2008 - 04/2003
4	Interleukin-15 (Interleukin 15)IBA 01/2021 - 07/2002
4	AntigensIBA 07/2007 - 08/2003
3	LigandsIBA 01/2021 - 01/2003
3	ChemokinesIBA 01/2021 - 07/2002
3	PerforinIBA 01/2019 - 04/2003
3	Vascular Endothelial Growth Factor CIBA 01/2018 - 07/2009
3	Messenger RNA (mRNA)IBA 03/2016 - 10/2004
3	interleukin-21 (interleukin 21)IBA 09/2006 - 02/2004
3	DNA VaccinesIBA 06/2006 - 04/2004
3	Interferon-gamma (Interferon, gamma)IBA 12/2005 - 06/2003
3	AntibodiesIBA 02/2005 - 04/2004
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2022 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 02/2022 - 03/2016
2	CXC ChemokinesIBA 01/2021 - 02/2004
2	InterferonsIBA 01/2017 - 05/2013
2	AndrogensIBA 01/2016 - 03/2011
2	Peptides (Polypeptides)IBA 08/2015 - 04/2004
2	Antineoplastic Agents (Antineoplastics)IBA 11/2010 - 08/2010
2	Interleukin-8 (Interleukin 8)IBA 10/2010 - 10/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2009 - 09/2006
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2004 - 07/2002
2	Immunoglobulin G (IgG)IBA 07/2003 - 05/2003
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2003 - 07/2002
1	8-hydroxyguanineIBA 09/2021
1	furanIBA 09/2021
1	Calcibiotic Root Canal SealerIBA 01/2021
1	TNF Receptor-Associated Factor 1IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	T-Cell Intracellular Antigen-1IBA 01/2019
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2019
1	Bevacizumab (Avastin)FDA Link 01/2017
1	Therapeutic UsesIBA 01/2017
1	Chimeric Antigen ReceptorsIBA 01/2017
1	Chromogranin AIBA 03/2016
1	Androgen Receptors (Androgen Receptor)IBA 01/2016
1	Glycoproteins (Glycoprotein)IBA 01/2016
1	OsteopontinIBA 01/2016
1	Interleukin-17 (Interleukin 17)IBA 10/2015
1	AzoxymethaneIBA 08/2015
1	Dextrans (Dextran)FDA Link 08/2015
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 02/2014
1	Epithelial Cell Adhesion MoleculeIBA 01/2014
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2014
1	Histocompatibility Antigens Class IIBA 05/2013
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2013
1	Zoledronic Acid (Zometa)FDA Link 05/2013
1	Propidium (Propidium Iodide)IBA 03/2012
1	Bromodeoxyuridine (BrdU)IBA 03/2012
1	Annexin A5IBA 03/2012
1	Hormones (Hormone)IBA 03/2011
1	Interleukin-23 (Interleukin 23)IBA 11/2010
1	CD13 Antigens (Alanine Aminopeptidase)IBA 10/2010
1	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 10/2009
1	Interleukin-7 (Interleukin 7)IBA 05/2009
1	IntegrinsIBA 11/2008
1	integrin beta5IBA 11/2008

Therapy/Procedure

5	Immunotherapy 01/2021 - 02/2006
4	Therapeutics 02/2015 - 10/2004
1	Intravenous Administration 01/2017
1	Prostatectomy (Retropubic Prostatectomy) 03/2011